SCHEMBL4732159

SCHEMBL4732159

Cc1cc2c(cc1S(=O)(=O)NC1CCN(C(=O)CCCC(=O)O)CC1)S(=O)(=O)c1ccccc1C2(C)C

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SFRP1 Q8N474 2/20 0.49
CCR8 P51685 17/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4731311 0.95 SFRP1 (0.48) SFRP1CCR8
SCHEMBL4730237 0.88 MEN1 (0.39) SFRP1CCR8
SCHEMBL4784267 0.87 SFRP1 (0.48) SFRP1CCR8
SCHEMBL4730981 0.86 SFRP1 (0.46) SFRP1
SCHEMBL4733321 0.83 CCR8 (0.47) SFRP1CCR8
SCHEMBL4733956 0.80 PIK3CD (0.36)
SCHEMBL4730240 0.80 CCR8 (0.39) SFRP1CCR8
SCHEMBL4733195 0.79 CCR8 (0.41) CCR8
SCHEMBL4733258 0.79 SFRP1 (0.51) SFRP1
SCHEMBL4736205 0.78 HTT (0.35) CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008061029-A1 ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE WYETH (US) 2008-05-22 WO disclosed