Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.42 |
| ▸ | CNR1 | P21554 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MARS1 | P56192 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731233 | 0.95 | LMNA (0.44) | CNR2CNR1LMNAMARS1ALDH1A1 | |
| SCHEMBL4729374 | 0.92 | CNR2 (0.36) | CNR2CNR1CYP1A2CYP2D6MAPT | |
| SCHEMBL4728429 | 0.90 | MARS1 (0.35) | CNR2CNR1CYP1A2CYP2D6MAPT | |
| SCHEMBL4730638 | 0.90 | MARS1 (0.43) | CNR2CNR1LMNAMARS1ALDH1A1 | |
| SCHEMBL4783366 | 0.90 | RIPK1 (0.35) | CNR2CNR1CYP1A2CYP2D6MAPT | |
| SCHEMBL4729440 | 0.89 | CNR1 (0.43) | CNR2CNR1LMNAMARS1 | |
| SCHEMBL4730418 | 0.89 | CNR2 (0.43) | CNR2CNR1LMNAMARS1 | |
| SCHEMBL4729313 | 0.89 | CNR1 (0.44) | CNR2CNR1MARS1 | |
| SCHEMBL4728972 | 0.89 | MARS1 (0.48) | CNR2CNR1MARS1 | |
| SCHEMBL4784498 | 0.87 | MARS1 (0.49) | CNR2CNR1MARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |