Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950698 | 1.00 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL28853816 | 0.89 | EPHX1 (0.45) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL24098427 | 0.78 | TAAR1 (0.40) | SLC6A2TAAR1SLC6A4SLC6A3CYP2A6 | |
| SCHEMBL9045670 | 0.78 | MAOB (0.46) | TAAR1MAOASLC6A4MAOB | |
| SCHEMBL10348476 | 0.78 | ANPEP (0.47) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL79728 | 0.77 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL2921309 | 0.77 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL10402865 | 0.77 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL79729 | 0.77 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL1263137 | 0.77 | EPHX1 (0.56) | EPHX1SLC6A2TAAR1MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7247246-A | — | — | None | — | — | JP | disclosed |
| US-9884891-B2 | KISS1R receptor agonist compounds and use thereof for inducing ovulation in mammals | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2018-02-06 | — | — | US | disclosed |
| US-9884891-B2 | KISS1R receptor agonist compounds and use thereof for inducing ovulation in mammals | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2018-02-06 | — | — | US | disclosed |
| US-9884891-B2 | KISS1R receptor agonist compounds and use thereof for inducing ovulation in mammals | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2018-02-06 | — | — | US | disclosed |
| US-20150361138-A1 | KISS1R RECEPTOR AGONIST COMPOUNDS AND USE THEREOF FOR INDUCING OVULATION IN MAMMALS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) | 2015-12-17 | — | — | US | disclosed |
| US-20150361138-A1 | KISS1R RECEPTOR AGONIST COMPOUNDS AND USE THEREOF FOR INDUCING OVULATION IN MAMMALS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) | 2015-12-17 | — | — | US | disclosed |
| US-20150361138-A1 | KISS1R RECEPTOR AGONIST COMPOUNDS AND USE THEREOF FOR INDUCING OVULATION IN MAMMALS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) | 2015-12-17 | — | — | US | disclosed |
| EP-2951200-A1 | KISS1R RECEPTOR AGONIST COMPOUNDS AND USE THEREOF FOR INDUCING OVULATION IN MAMMALS | Institut National de la Recherche Agronomique (FR) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014118318-A1 | KISS1R RECEPTOR AGONIST COMPOUNDS AND USE THEREOF FOR INDUCING OVULATION IN MAMMALS | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014118318-A1 | KISS1R RECEPTOR AGONIST COMPOUNDS AND USE THEREOF FOR INDUCING OVULATION IN MAMMALS | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2014-08-07 | — | — | WO | disclosed |
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-09-04 | — | — | US | disclosed |
| WO-2008033557-A2 | CLICK CHEMISTRY-DERIVED CYCLIC PEPTIDOMIMETICS AS INTEGRIN MARKERS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008033557-A2 | CLICK CHEMISTRY-DERIVED CYCLIC PEPTIDOMIMETICS AS INTEGRIN MARKERS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| JP-H07247246-A | 1-PHENYL-3-BUTYNE DERIVATIVE AND ITS PRODUCTION | DAICEL CHEM IND LTD | 1995-09-26 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | ITGB1, ITGAM, ITGB3 | EPHX1 3121/4885SLC6A2 4300/4885TAAR1 2827/4885 |
| US-20150361138-A1 | KISS1R RECEPTOR AGONIST COMPOUNDS AND USE THEREOF FOR INDUCING OVULATION IN MAMMALS | KISS1R, GNRHR, NPY1R | EPHX1 4458/4885SLC6A2 2436/4885TAAR1 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.