Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726516 | 0.89 | PSEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4726776 | 0.83 | PPARA (0.44) | MAPTALDH1A1PPARGPPARDPPARA | |
| SCHEMBL4729531 | 0.82 | MAPT (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4731807 | 0.80 | PPARA (0.41) | PPARGPPARDPPARAFFAR4 | |
| SCHEMBL4728561 | 0.79 | FABP4 (0.46) | MAPTALDH1A1PPARGPPARDPPARA | |
| SCHEMBL4730345 | 0.78 | PPARG (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4729524 | 0.77 | PLA2G2A (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4729526 | 0.77 | PLA2G2A (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4726347 | 0.77 | PGR (0.46) | PPARGPPARDPPARA | |
| SCHEMBL4726512 | 0.76 | PLA2G2A (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |