SCHEMBL4730644

SCHEMBL4730644

CCC(Oc1ccc(CC=NOCc2nc(-c3ccccc3)oc2C)cc1C)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.53
PPARA Q07869 16/20 0.48
PPARD Q03181 6/20 0.48
FFAR1 O14842 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4731241 0.94 PPARG (0.49) PPARGPPARAPPARD
SCHEMBL4726243 0.86 PPARA (0.38) PPARGPPARAPPARD
SCHEMBL4726349 0.85 PPARG (0.48) PPARGPPARAPPARD
SCHEMBL4726310 0.84 PPARG (0.67) PPARGPPARAPPARDFFAR1
SCHEMBL4728540 0.81 PPARG (0.56) PPARGPPARAPPARDFFAR1
SCHEMBL4728569 0.81 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL4728564 0.81 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL4727900 0.81 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL4729759 0.80 PPARA (0.41) PPARGPPARAPPARDFFAR1
SCHEMBL4726343 0.79 PPARG (0.53) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed