Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729056 | 0.95 | TACR1 (0.35) | TACR1SLC6A4CETP | |
| SCHEMBL4729974 | 0.81 | CCR2 (0.40) | TACR1 | |
| SCHEMBL4731996 | 0.70 | CCR2 (0.37) | TACR1 | |
| SCHEMBL4729901 | 0.69 | CETP (0.38) | TACR1CETP | |
| SCHEMBL4730989 | 0.69 | CETP (0.38) | TACR1CETP | |
| SCHEMBL4728683 | 0.69 | KDM4E (0.40) | TACR1CETP | |
| SCHEMBL4731245 | 0.68 | TACR1 (0.34) | TACR1SLC6A4 | |
| SCHEMBL3023612 | 0.68 | CCR2 (0.47) | TACR1 | |
| SCHEMBL3029909 | 0.68 | TACR1 (0.59) | TACR1 | |
| SCHEMBL4001725 | 0.67 | TACR1 (0.39) | TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |