Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 4/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | IDH1 | O75874 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733041 | 1.00 | GLS (0.42) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL19471088 | 0.86 | IDH1 (0.42) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL17870955 | 0.86 | IDH1 (0.42) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL29053815 | 0.84 | LMNA (0.44) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL29053818 | 0.84 | LMNA (0.44) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL17870942 | 0.81 | GLS (0.46) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL8138150 | 0.81 | HDAC1 (0.44) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL266818 | 0.81 | GLS (0.46) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL12333636 | 0.81 | GLS (0.46) | GLSSCD5NPC1LMNATP53 | |
| SCHEMBL2065159 | 0.79 | GLS (0.43) | GLSSCD5NPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008034032-A2 | BETA-LACTAM CANNABINOID RECEPTOR MODULATORS | AZEVAN PHARMACEUTICALS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| EP-0362902-B1 | Process and intermediates for beta-lactam antibiotics | HARVARD COLLEGE (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5091525-A | 7beta- 2'-(R)-2'-(p-hydroxyphenyl-2'-amino-acetamido!-3-chloro -3-(1-carbadethiacephem)-4-carboxylic acid | ELI LILLY AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |