SCHEMBL4732018

SCHEMBL4732018

CC(C)(C)OOOC(=O)C(=CC(=O)O)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7161015 0.84
SCHEMBL5005110 0.83
SCHEMBL4733014 0.83
SCHEMBL17364120 0.79 ALDH1A1 (0.32) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL4732197 0.79 ALDH1A1 (0.32) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL11128178 0.79
SCHEMBL4732096 0.78 MAPK1 (0.44) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL10728643 0.78 ALDH1A1 (0.34) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL8994049 0.76 DGAT1 (0.31)
SCHEMBL8994053 0.76 DGAT1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080250739-A1 FOAMED PLASTIC STRUCTURES NOVA CHEMICALS INC. (US) 2008-10-16 US claimed
US-20080250739-A1 FOAMED PLASTIC STRUCTURES NOVA CHEMICALS INC. (US) 2008-10-16 US disclosed
WO-2008057705-A1 FOAMED PLASTIC STRUCTURES NOVA CHEMICALS INC. (US) 2008-05-15 WO disclosed
US-6127325-A GRAFT COPOLYMER OF AN OIL-SOLUBLE OLEFIN POLYMER AND OF A COPOLYMER (B) OF A MONOMER HAVING A PEROXIDE BOND WITH (METH)ACRYLATE; OR COPOLYMER (C) OF A PEROXIDE CONTAINING MONOMER AND SPECIFIED MONOMERS; NO PHASE SEPARATION NOF CORPORATION (JP) 2000-10-03 US disclosed
US-6093781-A STYRENIC MONOMER COPOLYMERIZED WITH NEW CLASS OF INITIATORS THAT CONTAIN BOTH A COPOLYMERIZABLE DOUBLE BOND AND AN ORGANIC PEROXIDE MOIETY; HIGH SPEED THERMOFORMING THE DOW CHEMICAL COMPANY (US) 2000-07-25 US disclosed
EP-0785964-B1 NON-LINEAR STYRENIC POLYMER-BASED FOAMS DOW CHEMICAL CO (US) 1999-04-14 EP disclosed
US-5830924-A LOW DENSITY CLOSED CELL, BLOWING AGENTS THE DOW CHEMICAL COMPANY (US) 1998-11-03 US disclosed
EP-0872539-A1 VISCOSITY INDEX IMPROVER, PROCESS FOR PREPARING THE SAME AND LUBRICATING OIL COMPOSITION NOF CORPORATION (JP) 1998-10-21 EP disclosed
EP-0785957-B1 NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM DOW CHEMICAL CO (US) 1998-05-20 EP disclosed
EP-0785957-A1 NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1997-07-30 EP disclosed
EP-0785964-A1 NON-LINEAR STYRENIC POLYMER-BASED FOAMS THE DOW CHEMICAL COMPANY (US) 1997-07-30 EP disclosed
WO-1996011962-A1 NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1996-04-25 WO disclosed
WO-1996011970-A1 NON-LINEAR STYRENIC POLYMER-BASED FOAMS THE DOW CHEMICAL COMPANY (US) 1996-04-25 WO disclosed