Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994053 | 1.00 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL7161015 | 0.82 | — | — | |
| SCHEMBL28594951 | 0.81 | — | — | |
| SCHEMBL65755 | 0.80 | — | — | |
| SCHEMBL1323711 | 0.80 | — | — | |
| SCHEMBL11128178 | 0.77 | — | — | |
| SCHEMBL4732018 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL9709301 | 0.75 | — | — | |
| SCHEMBL30661728 | 0.74 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL3630555 | 0.74 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724573-A1 | PYRIMIDINONES AS ANTIARTHRITIC AND ANTI-INFLAMMATORIES | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011235-A1 | PYRIMIDINONES AS ANTIARTHRITIC AND ANTI-INFLAMMATORIES | THE UPJOHN COMPANY (US) | 1995-04-27 | — | — | WO | disclosed |