Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 18/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | WNT3 | P56703 | 5/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734093 | 0.89 | SFRP1 (0.53) | SFRP1KDM4EHSD17B10WNT3 | |
| SCHEMBL4734362 | 0.87 | SFRP1 (0.64) | SFRP1WNT3MGLL | |
| SCHEMBL4733149 | 0.79 | SFRP1 (0.48) | SFRP1WNT3 | |
| SCHEMBL4738622 | 0.76 | SFRP1 (0.61) | SFRP1WNT3 | |
| SCHEMBL4733299 | 0.76 | SFRP1 (0.64) | SFRP1 | |
| SCHEMBL4731611 | 0.75 | SFRP1 (0.69) | SFRP1WNT3 | |
| SCHEMBL4735241 | 0.75 | SFRP1 (0.62) | SFRP1WNT3 | |
| SCHEMBL4737077 | 0.75 | SFRP1 (0.68) | SFRP1WNT3 | |
| SCHEMBL4786060 | 0.75 | SFRP1 (0.69) | SFRP1WNT3 | |
| SCHEMBL4735995 | 0.74 | SFRP1 (0.63) | SFRP1WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |