SCHEMBL4732119

SCHEMBL4732119

Cc1ccc(S(=O)(=O)OC(C=O)c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.54
PIR O00625 1/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CNR2 P34972 1/20 0.42
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4733624 0.84 VDR (0.42) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL1822341 0.81 ALDH1A1 (0.44) ARPIRCA12CA2CNR2
SCHEMBL4730901 0.80 ALDH1A1 (0.46) NPC1HPGDRAB9ASMN1; SMN2LMNA
SCHEMBL2535587 0.79 AR (0.54) ARPIRCA12CA1CA2
SCHEMBL11686423 0.77 AR (0.54) ARPIRCA12CA1CA2
SCHEMBL3274194 0.77 AR (0.57) ARPIRCA12CA1CA2
SCHEMBL4728806 0.77 HTT (0.43) SMN1; SMN2LMNA
SCHEMBL4733846 0.76 UTS2R (0.40) SMN1; SMN2CNR2LMNACYP1A2CYP3A4
SCHEMBL4731994 0.76 ACHE (0.39) LMNA
SCHEMBL10983891 0.76 AR (0.58) ARPIRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008054155-A1 METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-05-08 WO disclosed