⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5932369 | 0.87 | THRB (0.35) | — | |
| SCHEMBL5932784 | 0.85 | — | — | |
| SCHEMBL5932653 | 0.83 | DNM1 (0.33) | — | |
| SCHEMBL5911574 | 0.75 | THRB (0.40) | — | |
| SCHEMBL5932498 | 0.75 | CA1 (0.31) | — | |
| SCHEMBL46524 | 0.72 | THRB (0.50) | — | |
| SCHEMBL25094 | 0.72 | — | — | |
| SCHEMBL5666168 | 0.72 | THRB (0.50) | — | |
| SCHEMBL5932417 | 0.71 | ADRB2 (0.38) | — | |
| SCHEMBL5666845 | 0.71 | THRB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145585-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-04 | — | — | WO | claimed |
| EP-3666767-B1 | PHTHALAZINONE DERIVATIVES, METHOD FOR THEIR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING THEM, AND THEIR USE | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2021-12-01 | — | — | EP | claimed |
| US-11040952-B2 | Phthalazinone compound, method for preparation thereof, pharmaceutical composition thereof, and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2021-06-22 | — | — | US | claimed |
| CN-109134429-B | Phthalazinone compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2021-06-01 | — | — | CN | claimed |
| EP-3666767-A1 | PYRIDAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2020-06-17 | — | — | EP | claimed |
| US-20200181109-A1 | PHTHALAZINONE COMPOUND, METHOD FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2020-06-11 | — | — | US | claimed |
| US-20060292326-A1 | Optical data store comprising a cobalt phthalocyanine with an axial substituent and axial ligand in an information photoinscribtible layer | LANXESS DEUTSCHLAND GMBH (DE) | 2006-12-28 | — | — | US | claimed |
| EP-1563014-A1 | OPTICAL DATA MEMORIES COMPRISING COBALT PHTALOCYANIN WITH AN AXIAL SUBSTITUENT AND AXIAL LIGAND IN AN INFORMATION PHOTOINSCRIBTIBLE LAYER | LANXESS Deutschland GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046253-A1 | OPTICAL DATA MEMORIES COMPRISING COBALT PHTALOCYANIN WITH AN AXIAL SUBSTITUENT AND AXIAL LIGAND IN AN INFORMATION PHOTOINSCRIBTIBLE LAYER | LANXESS DEUTSCHLAND GMBH (DE) | 2004-06-03 | — | — | WO | claimed |
| US-6737142-B2 | FOR USE AS WRITE-ONCE COMPACT DISK (CD-R) | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-18 | — | — | US | claimed |
| US-20020127366-A1 | Optical data stores containing a Co-phthalocyanine complex in the information layer recordable using light | LANXESS DEUTSCHLAND GMBH (DE) | 2002-09-12 | — | — | US | claimed |
| WO-2002025205-A1 | OPTICAL DATA STORAGE DEVICE CONTAINING A CO-PHTHALOCYANIN COMPLEX IN THE OPTICALLY WRITABLE INFORMATION LAYER | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-28 | — | — | WO | claimed |
| WO-2001002355-A2 | INDOLE SYNTHESIS | AXYS PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | claimed |
| US-5495031-A | Process for the production of 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1996-02-27 | — | — | US | claimed |
| US-5466684-A | 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1995-11-14 | — | — | US | claimed |
| US-5328902-A | Antibiotics | AMERICAN CYANAMID CO. (US) | 1994-07-12 | — | — | US | claimed |
| EP-0062827-B1 | NOVEL BENZAMIDE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD (JP) | 1986-07-23 | — | — | EP | claimed |
| EP-0006227-B1 | ANTITHROMBOTIC PHARMACEUTICAL PREPARATION CONTAINING 2,2'-DITHIOBIS BENZAMIDE DERIVATIVES AND NEW 2,2'-DITHIOBIS BENZAMIDE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-12-27 | — | — | EP | claimed |
| EP-0062827-A2 | Novel benzamide derivatives | KYOWA HAKKO KOGYO CO., LTD (JP) | 1982-10-20 | — | — | EP | claimed |
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | claimed |