Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899627 | 0.79 | LMNA (0.54) | LMNACES2CES1TSHRL3MBTL1 | |
| SCHEMBL4733260 | 0.77 | CCNE2 (0.39) | PLA2G4ATDP1ALDH1A1 | |
| SCHEMBL4734884 | 0.75 | HCAR2 (0.38) | TSHRNAAAALDH1A1 | |
| SCHEMBL8985110 | 0.75 | LMNA (0.53) | LMNACES2CES1TSHRL3MBTL1 | |
| SCHEMBL3482698 | 0.74 | ALDH1A1 (0.54) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL6394012 | 0.74 | ALDH1A1 (0.54) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL11274535 | 0.74 | ALDH1A1 (0.54) | LMNAL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL4733824 | 0.74 | TDP1 (0.51) | LMNACES1TSHRL3MBTL1TDP1 | |
| SCHEMBL1581592 | 0.74 | LMNA (0.51) | LMNACES2CES1TSHRTDP1 | |
| SCHEMBL27904265 | 0.73 | CES2 (0.53) | LMNACES2CES1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | claimed |