Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731943 | 0.81 | ADRB2 (0.35) | SLC6A4PTGS2ALDH1A1CYP3A4IDO1 | |
| SCHEMBL12497515 | 0.80 | SLC6A2 (0.45) | SLC6A3SLC6A2SLC6A4LMNAALDH1A1 | |
| SCHEMBL4728454 | 0.79 | ACP3 (0.36) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4731012 | 0.76 | UGT2B7 (0.42) | SLC6A3SLC6A2SLC6A4LMNACYP2D6 | |
| SCHEMBL4731665 | 0.75 | ALDH1A1 (0.37) | PTGS2ALDH1A1IDO1TDO2 | |
| SCHEMBL17831446 | 0.74 | LMNA (0.41) | SLC6A3SLC6A2SLC6A4LMNAPTGS2 | |
| SCHEMBL19717861 | 0.74 | KMT2A (0.37) | SLC6A2LMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL4731661 | 0.73 | CA1 (0.42) | PTGS2ALDH1A1 | |
| SCHEMBL3741260 | 0.73 | AKR1C3 (0.41) | SLC6A3LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7497307 | 0.73 | SLC6A2 (0.37) | SLC6A3SLC6A2SLC6A4LMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008054155-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |