Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733533 | 0.90 | SCD (0.43) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL4732132 | 0.90 | KMT2A (0.43) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL4732699 | 0.87 | SCD (0.48) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL4730349 | 0.79 | SLC6A7 (0.43) | MEN1KMT2AKDM4ESLC6A7CNR1 | |
| SCHEMBL14175660 | 0.76 | SLC6A7 (0.44) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL4732906 | 0.74 | SLC6A7 (0.53) | MEN1KMT2AKDM4ESLC6A7CNR1 | |
| SCHEMBL4729599 | 0.73 | KMT2A (0.43) | MEN1KMT2AKDM4ESCDCNR1 | |
| SCHEMBL4731971 | 0.72 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1SCD | |
| SCHEMBL5102741 | 0.72 | SLC6A7 (0.51) | KDM4EALDH1A1SLC6A7CNR1CNR2 | |
| SCHEMBL4734023 | 0.72 | SLC6A7 (0.51) | KDM4ESLC6A7CNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008058064-A1 | AMINE-LINKED MULTICYCLIC COMPOUNDS AS INHIBITORS OF THE PROLINE TRANSPORTER | LEXICON PHARMACEUTICALS, INC. (US) | 2008-05-15 | — | — | WO | claimed |
| WO-2008058064-A1 | AMINE-LINKED MULTICYCLIC COMPOUNDS AS INHIBITORS OF THE PROLINE TRANSPORTER | LEXICON PHARMACEUTICALS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |