Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730349 | 0.79 | SLC6A7 (0.43) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL4732131 | 0.78 | ALDH1A1 (0.46) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL4732132 | 0.78 | KMT2A (0.43) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL4732421 | 0.78 | KMT2A (0.43) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL4731971 | 0.78 | MEN1 (0.47) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL5096292 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL4729979 | 0.75 | MALT1 (0.48) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL4731869 | 0.74 | CNR1 (0.49) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL4732463 | 0.73 | MEN1 (0.46) | KMT2AMEN1CNR1CNR2KDM4E | |
| SCHEMBL4731689 | 0.72 | KDM4E (0.48) | KMT2AMEN1CNR1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008058064-A1 | AMINE-LINKED MULTICYCLIC COMPOUNDS AS INHIBITORS OF THE PROLINE TRANSPORTER | LEXICON PHARMACEUTICALS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |