SCHEMBL4732476

SCHEMBL4732476

CCOC(OCC)[SiH2]C(C)C=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18549788 0.77 LMNA (0.36) LMNATHRB
SCHEMBL2931933 0.74 THRB (0.47) LMNATHRB
SCHEMBL331067 0.72 LMNA (0.45) LMNATHRB
SCHEMBL15611680 0.72 LMNA (0.45) LMNATHRB
SCHEMBL23890643 0.69
SCHEMBL1562985 0.69
SCHEMBL28980315 0.69 LMNA (0.41) LMNATHRB
SCHEMBL28308317 0.69 LMNA (0.41) LMNATHRB
SCHEMBL27456565 0.69 LMNA (0.41) LMNATHRB
SCHEMBL23780009 0.67 ADH1B (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008063134-A1 METHOD OF PRODUCING A PATTERN OF DISCRIMINATIVE WETTABILITY AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed