Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | HPD | P32754 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609062 | 0.76 | PDK2 (0.34) | TSHRALDH1A1LMNARAB9A | |
| SCHEMBL5326393 | 0.72 | KDM4E (0.58) | MEN1TSHRKMT2APTGDR2ALDH1A1 | |
| SCHEMBL1601510 | 0.70 | CES2 (0.39) | MEN1TSHRKMT2APTGDR2ALDH1A1 | |
| SCHEMBL1601508 | 0.68 | CFTR (0.40) | MEN1TSHRKMT2APTGDR2ALDH1A1 | |
| SCHEMBL26679561 | 0.68 | HPD (0.67) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL1341192 | 0.68 | KDM4E (0.47) | MEN1TSHRKMT2AALDH1A1RXFP1 | |
| SCHEMBL1600945 | 0.67 | CFTR (0.39) | MEN1TSHRKMT2APTGDR2ALDH1A1 | |
| SCHEMBL9156406 | 0.65 | GAA (0.49) | MEN1TSHRKMT2AALDH1A1RXFP1 | |
| SCHEMBL6896656 | 0.65 | MEN1 (0.51) | MEN1TSHRKMT2AALDH1A1KDM4E | |
| SCHEMBL26081057 | 0.65 | HSD11B1 (0.58) | MEN1TSHRKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996564-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | Pfizer Products Incorporated (US) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007105050-A1 | DIBENZYL AMINE COMPOUNDS AND DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | disclosed |