Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | HTR7 | P34969 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733346 | 1.00 | AQP1 (0.42) | AQP1TDP1L3MBTL1HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4729050 | 0.99 | AQP1 (0.41) | AQP1TDP1L3MBTL1HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4729053 | 0.99 | AQP1 (0.41) | AQP1TDP1L3MBTL1HTR1AHTR7 | |
| SCHEMBL4622511 | 0.80 | AQP1 (0.59) | AQP1TDP1L3MBTL1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL4622531 | 0.79 | AQP1 (0.58) | AQP1TDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL14271068 | 0.78 | AQP1 (0.44) | AQP1TDP1L3MBTL1HTR1AHTR7 | |
| SCHEMBL8223394 | 0.76 | AQP1 (0.46) | AQP1TDP1L3MBTL1DRD2DRD4 | |
| SCHEMBL4732206 | 0.76 | L3MBTL1 (0.42) | AQP1TDP1L3MBTL1SLC6A3FABP4 | |
| SCHEMBL8258102 | 0.75 | AQP1 (0.42) | AQP1TDP1L3MBTL1HTR1AHTR7 | |
| SCHEMBL8255634 | 0.75 | AQP1 (0.42) | AQP1TDP1L3MBTL1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052088-A1 | CHROMANE DERIVATIVES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |