Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.39 |
| ▸ | RELA | Q04206 | 7/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | AQP1 | P29972 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213736 | 0.85 | SMN1; SMN2 (0.41) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL4732072 | 0.85 | TDP1 (0.40) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL4731714 | 0.85 | TDP1 (0.40) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL4729890 | 0.85 | SMN1; SMN2 (0.41) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL8203895 | 0.85 | SMN1; SMN2 (0.41) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL24496712 | 0.78 | NFKB1 (0.41) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL15882879 | 0.78 | NFKB1 (0.41) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL29588222 | 0.78 | NFKB1 (0.41) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL24496718 | 0.78 | NFKB1 (0.41) | L3MBTL1TDP1NFKB1NFKB2RELA | |
| SCHEMBL4733346 | 0.76 | AQP1 (0.42) | L3MBTL1TDP1SLC6A3AQP1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052088-A1 | CHROMANE DERIVATIVES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008052088-A1 | CHROMANE DERIVATIVES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |