Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736951 | 0.88 | ABL1 (0.49) | ALDH1A1HPGDHTTABL1KDM4E | |
| SCHEMBL21392831 | 0.84 | KDM4E (0.70) | ALDH1A1HPGDKDM4EATMGLA | |
| SCHEMBL5928755 | 0.81 | ABL1 (0.58) | ALDH1A1HPGDHTTABL1KDM4E | |
| SCHEMBL28549394 | 0.79 | CFTR (0.56) | ALDH1A1HPGDHTTKDM4EATM | |
| SCHEMBL4736645 | 0.78 | HPGD (0.68) | ALDH1A1HPGDHTTKDM4EATM | |
| SCHEMBL23044925 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDHTTABL1KDM4E | |
| SCHEMBL5875315 | 0.78 | ABL1 (0.62) | ALDH1A1HPGDHTTABL1KDM4E | |
| SCHEMBL31162468 | 0.78 | MEN1 (0.61) | MEN1KMT2APOLBMAPT | |
| SCHEMBL7467356 | 0.78 | KMT2A (0.56) | ALDH1A1HPGDHTTABL1KDM4E | |
| SCHEMBL4070159 | 0.78 | KDM4E (0.71) | ALDH1A1HPGDHTTABL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |