Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733402 | 0.88 | ALDH1A1 (0.59) | ABL1KDM4EHPGDALDH1A1HTT | |
| SCHEMBL3265331 | 0.85 | CA12 (0.56) | KDM4EHSD17B10HPGDALDH1A1HTT | |
| SCHEMBL3267660 | 0.82 | PTPRC (0.44) | KDM4EHSD17B10HPGDALDH1A1HTT | |
| SCHEMBL21431006 | 0.82 | TGM2 (0.56) | KDM4EHSD17B10HPGDALDH1A1HTT | |
| SCHEMBL5928677 | 0.81 | KDM4E (0.71) | ABL1KDM4EHSD17B10ALDH1A1HTT | |
| SCHEMBL4736645 | 0.78 | HPGD (0.68) | KDM4EHSD17B10HPGDALDH1A1HTT | |
| SCHEMBL11336614 | 0.78 | EGFR (0.59) | KDM4EHPGDALDH1A1RXFP1MAPT | |
| SCHEMBL4358899 | 0.78 | KDM4E (0.67) | ABL1KDM4EHSD17B10ALDH1A1GLA | |
| SCHEMBL31162463 | 0.78 | EGFR (0.59) | KDM4EHPGDALDH1A1RXFP1MAPT | |
| SCHEMBL2534951 | 0.78 | SMN1; SMN2 (0.46) | ABL1KDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |