Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 4/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TGM1 | P22735 | 1/20 | 0.41 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179193 | 0.82 | TGM2 (0.53) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL4734509 | 0.78 | HSD17B10 (0.41) | HSD17B10CA12CA1CA2CA7 | |
| Acrylamide SCHEMBL28343508 | 0.76 | TGM2 (0.47) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL4846741 | 0.75 | HSD17B10 (0.39) | HSD17B10ALDH1A1GAAKDM4EPOLB | |
| SCHEMBL935778 | 0.71 | HSD17B10 (0.49) | HSD17B10CA12CA1CA2CA7 | |
| SCHEMBL17627594 | 0.71 | AKR1C4 (0.60) | LMNAHSD17B10CA12CA1CA2 | |
| SCHEMBL4734500 | 0.70 | L3MBTL1 (0.50) | ALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL3856537 | 0.70 | ALDH1A1 (0.46) | LMNAALDH1A1GAAPOLB | |
| SCHEMBL4803910 | 0.70 | ALDH1A1 (0.46) | HSD17B10ALDH1A1GAAKDM4EPOLB | |
| SCHEMBL3265331 | 0.70 | CA12 (0.56) | TGM2LMNAHSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |