Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NCF1 | P14598 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732942 | 0.87 | MOK (0.51) | NPSR1KMT2AALDH1A1HPGDGBA1 | |
| SCHEMBL4731636 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTMOKLMNANCF1 | |
| SCHEMBL4729660 | 0.77 | MOK (0.53) | ALDH1A1MAPTMOKNCF1PIK3CA | |
| Hydrochloric Acid SCHEMBL4730661 | 0.76 | MOK (0.52) | ALDH1A1MAPTMOKNCF1PIK3CA | |
| SCHEMBL5241851 | 0.74 | NCF1 (0.64) | NPSR1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL15503740 | 0.73 | KMT2A (1.00) | NPSR1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL196063 | 0.71 | RXFP1 (0.60) | KMT2AHPGDMAPTLMNANPC1 | |
| SCHEMBL17302112 | 0.71 | NCF1 (0.56) | KMT2AALDH1A1HPGDLMNANCF1 | |
| SCHEMBL17302052 | 0.71 | NCF1 (0.56) | KMT2AALDH1A1HPGDLMNANCF1 | |
| SCHEMBL14332218 | 0.71 | GBA1 (1.00) | NPSR1KMT2AALDH1A1HPGDGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |