Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | HTR7 | P34969 | 7/20 | 0.47 |
| ▸ | CCR8 | P51685 | 10/20 | 0.45 |
| ▸ | WNT3 | P56703 | 1/20 | 0.42 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4617617 | 0.84 | SFRP1 (0.57) | WNT3SFRP1 | |
| SCHEMBL15614423 | 0.84 | L3MBTL1 (0.51) | DRD2HTR6HTR1AHTR7 | |
| SCHEMBL4736968 | 0.83 | CCR8 (0.52) | CCR8 | |
| SCHEMBL4802785 | 0.81 | HTR1A (0.48) | HTR1AHTR7CCR8WNT3SFRP1 | |
| SCHEMBL15916163 | 0.81 | MAPT (0.65) | HTR1AHTR7CCR8WNT3SFRP1 | |
| SCHEMBL4784223 | 0.80 | HTR1A (0.42) | DRD2HTR6HTR1AHTR7CCR8 | |
| SCHEMBL4733156 | 0.79 | SFRP1 (0.59) | DRD2HTR6HTR1AHTR7CCR8 | |
| SCHEMBL4736346 | 0.79 | SFRP1 (0.47) | WNT3SFRP1 | |
| SCHEMBL27900241 | 0.79 | CCR8 (0.53) | DRD2HTR6HTR7CCR8 | |
| SCHEMBL6102396 | 0.78 | SFRP1 (0.51) | WNT3SFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |