Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734703 | 0.91 | BRD4 (0.38) | BRD4KMT2ARXFP1ALDH1A1PPARG | |
| SCHEMBL4733561 | 0.81 | KMT2A (0.35) | LMNAKMT2AALDH1A1KDM4EGAA | |
| Trifluoroacetic Acid SCHEMBL4737130 | 0.77 | NOTUM (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL4737901 | 0.77 | BRD4 (0.51) | BRD4GAATSHR | |
| SCHEMBL7716549 | 0.74 | BRD4 (0.36) | BRD4KMT2ARXFP1ALDH1A1KDM4E | |
| SCHEMBL13735175 | 0.70 | RXFP1 (0.36) | BRD4LMNAKMT2ARXFP1KDM4E | |
| Trifluoroacetic Acid SCHEMBL3583791 | 0.69 | KDM4E (0.39) | LMNARXFP1ALDH1A1KDM4E | |
| Trifluoroacetic Acid SCHEMBL16700571 | 0.68 | ALDH1A1 (0.44) | BRD4LMNAKMT2ARXFP1ALDH1A1 | |
| SCHEMBL13732305 | 0.67 | PKM (0.36) | BRD4LMNARXFP1KDM4ESMN1; SMN2 | |
| SCHEMBL13736015 | 0.67 | PKM (0.36) | BRD4LMNARXFP1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |