Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 3/20 | 0.31 |
| ▸ | CASP7 | P55210 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | KPNA2 | P52292 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4733563 | 0.81 | BRD4 (0.34) | KMT2AKDM4EALDH1A1GAALMNA | |
| SCHEMBL4737129 | 0.78 | ACACB (0.31) | GABRA2GABRB2 | |
| SCHEMBL4734703 | 0.77 | BRD4 (0.38) | KMT2AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL4737896 | 0.77 | BRD4 (0.41) | ALDH1A1LMNAGABRA2GABRB2 | |
| SCHEMBL16268982 | 0.68 | KMT2A (0.44) | KMT2AKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4734971 | 0.63 | PTGER1 (0.43) | HIF1AGABRA2GABRB2 | |
| SCHEMBL4735031 | 0.62 | SCD (0.32) | — | |
| SCHEMBL3020362 | 0.62 | KMT2A (0.46) | KMT2AKDM4ELMNAGABRB2 | |
| SCHEMBL4418287 | 0.61 | ALDH1A1 (0.66) | KMT2AALDH1A1LMNATHRB | |
| SCHEMBL25394222 | 0.60 | PDE10A (0.42) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |