SCHEMBL4733728

SCHEMBL4733728

O=C(O)CC(=O)[C@H]1CCCN1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.44
NOS2 P35228 2/20 0.42
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
DPP4 P27487 4/20 0.40
MEN1 O00255 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
DPP7 Q9UHL4 2/20 0.39
DPP8 Q6V1X1 2/20 0.39
DPP9 Q86TI2 2/20 0.39
CTSC P53634 1/20 0.38
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
FAP Q12884 1/20 0.38
TLR2 O60603 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4733724 1.00 PRCP (0.44) PRCPNOS2NOS3NOS1DPP4
SCHEMBL4733722 1.00 PRCP (0.44) PRCPNOS2NOS3NOS1DPP4
SCHEMBL11214576 0.94 PRCP (0.39) PRCPNOS2NOS3NOS1DPP4
SCHEMBL29471063 0.82 PRCP (0.42) PRCPNOS2NOS3NOS1DPP4
SCHEMBL1969952 0.82 NOS2 (0.50) PRCPNOS2NOS3NOS1DPP4
SCHEMBL1969951 0.82 NOS2 (0.50) PRCPNOS2NOS3NOS1DPP4
SCHEMBL4012939 0.82 PRCP (0.46) PRCPNOS2NOS3NOS1DPP4
SCHEMBL2496026 0.82 PRCP (0.46) PRCPNOS2NOS3NOS1DPP4
SCHEMBL4685341 0.82 PRCP (0.46) PRCPNOS2NOS3NOS1DPP4
SCHEMBL2496024 0.79 PRCP (0.41) PRCPNOS2NOS3NOS1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220195739-A1 SCUFF RESISTANT SURFACE COVERINGS TARKETT GDL (LU) 2022-06-23 US disclosed
EP-3972838-A1 SCUFF RESISTANT SURFACE COVERINGS Tarkett GDL (LU) 2022-03-30 EP disclosed
US-20080280824-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER OR NEURODEGENERATIVE DISEASE WITH PEPTIDE BASED MICROTUBULE STABILIZERS OR INHIBITORS UNIVERSITY OF WASHINGTON (US) 2008-11-13 US disclosed
WO-2008070586-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF PROTEIN MISFOLDING AND PROTEIN AGGREGATION DISEASES UNIVERSITY OF WASHINGTON (US) 2008-06-12 WO disclosed
US-20070185028-A1 Compositions and methods for treatment of protein misfolding and protein aggregation diseases NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-08-09 US disclosed