Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47336 | 0.98 | KMT2A (0.48) | KMT2AHTTALDH1A1EPHX2LMNA | |
| SCHEMBL14282244 | 0.81 | KMT2A (0.50) | KMT2AHTTALDH1A1EPHX2HSD11B1 | |
| SCHEMBL14941550 | 0.79 | KMT2A (0.48) | KMT2AHTTALDH1A1EPHX2HSD11B1 | |
| SCHEMBL47346 | 0.78 | HTT (0.66) | KMT2AHTTSMN1; SMN2GAA | |
| SCHEMBL14037284 | 0.78 | TPSAB1 (0.60) | HTTEPHX2LMNA | |
| SCHEMBL5524889 | 0.77 | KMT2A (0.46) | KMT2AHTTALDH1A1EPHX2HSD11B1 | |
| SCHEMBL966438 | 0.77 | KMT2A (0.78) | KMT2AHTTALDH1A1LMNANPC1 | |
| SCHEMBL17273858 | 0.77 | KMT2A (0.78) | KMT2AHTTALDH1A1LMNANPC1 | |
| SCHEMBL22559960 | 0.77 | KMT2A (0.46) | KMT2AHTTALDH1A1EPHX2HSD11B1 | |
| SCHEMBL4803949 | 0.77 | KMT2A (0.78) | KMT2AHTTALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |