Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47339 | 0.98 | KMT2A (0.46) | KMT2AALDH1A1EPHX2HTTLMNA | |
| SCHEMBL47346 | 0.80 | HTT (0.66) | KMT2AHTT | |
| SCHEMBL7804748 | 0.78 | KMT2A (0.50) | KMT2AALDH1A1EPHX2HTTATM | |
| SCHEMBL14282244 | 0.78 | KMT2A (0.50) | KMT2AALDH1A1EPHX2HTTHSD11B1 | |
| SCHEMBL14941550 | 0.76 | KMT2A (0.48) | KMT2AALDH1A1EPHX2HTTHSD11B1 | |
| SCHEMBL5522397 | 0.76 | KMT2A (0.48) | KMT2AALDH1A1EPHX2HTTATM | |
| SCHEMBL965286 | 0.76 | KMT2A (0.82) | KMT2AALDH1A1EPHX2HTTLMNA | |
| SCHEMBL9092175 | 0.76 | KMT2A (0.48) | KMT2AALDH1A1EPHX2HTTATM | |
| SCHEMBL17273967 | 0.76 | EPHX2 (0.47) | KMT2AALDH1A1EPHX2HTTTPSAB1 | |
| SCHEMBL14037284 | 0.76 | TPSAB1 (0.60) | EPHX2HTTTPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582696-B1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |