Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442633 | 0.84 | HTT (0.62) | HTTSMN1; SMN2PKMKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10599246 | 0.82 | HTT (0.60) | HTTSMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL27570688 | 0.81 | HTT (0.68) | HTTSMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL47336 | 0.80 | KMT2A (0.48) | HTTKMT2A | |
| Oxalic Acid SCHEMBL28342918 | 0.80 | HTT (0.57) | HTTSMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL968488 | 0.79 | HTT (1.00) | HTTSMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL1233491 | 0.79 | HTT (0.66) | HTTSMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL47339 | 0.78 | KMT2A (0.46) | HTTSMN1; SMN2KMT2AGAA | |
| Sulfuric Acid SCHEMBL7429284 | 0.78 | HTT (0.55) | HTTSMN1; SMN2PKMKMT2AMEN1 | |
| SCHEMBL1446597 | 0.78 | HTT (0.64) | HTTSMN1; SMN2PKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |