Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445918 | 0.82 | HTR6 (0.63) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL3644542 | 0.75 | HTR6 (1.00) | HTR6CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL27782844 | 0.74 | SRR (0.54) | — | |
| Acetic Acid SCHEMBL27782836 | 0.74 | SRR (0.51) | — | |
| SCHEMBL1651879 | 0.73 | HTR6 (0.74) | HTR6CA12CA1CA2CA9 | |
| Sulfuric Acid SCHEMBL28299133 | 0.73 | ALPI (0.51) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| Sulfuric Acid SCHEMBL10864212 | 0.72 | ALPI (0.54) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL132409 | 0.72 | ALPI (0.61) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL616963 | 0.72 | ALPI (0.61) | SLC1A3SLC1A2SLC1A1MEN1KMT2A | |
| SCHEMBL132790 | 0.72 | ALPI (0.61) | SLC1A3SLC1A2SLC1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |