Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26325 | 0.83 | TSHR (0.48) | LMNASMN1; SMN2GPR35ALDH1A1TSHR | |
| Water SCHEMBL28995322 | 0.82 | TSHR (0.46) | LMNASMN1; SMN2GPR35ALDH1A1TSHR | |
| SCHEMBL205059 | 0.80 | MEN1 (1.00) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL12095462 | 0.78 | MEN1 (0.95) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL12933087 | 0.73 | MEN1 (0.84) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL6257261 | 0.71 | SNCA (0.33) | MEN1KMT2AHTTLMNATSHR | |
| SCHEMBL3044183 | 0.71 | ALDH1A1 (0.44) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL10383515 | 0.71 | TSHR (0.46) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL887743 | 0.71 | TSHR (0.48) | MEN1KMT2AHTTLMNASMN1; SMN2 | |
| Edetic Acid SCHEMBL28237466 | 0.70 | KCNH2 (0.41) | MEN1KMT2AHTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837661-A | Melanocortin receptor ligands | 益普生制药股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-103316345-B | The application of melanocortin treatment insulin sensitivity | IPSEN PHARMA S.A.S. (FR) | 2016-05-18 | — | — | CN | disclosed |
| CN-103755786-B | Melanocortin receptor ligands | IPSEN PHARMA S. A. S. (FR) | 2016-05-11 | — | — | CN | disclosed |
| CN-105111302-A | Auxin gastrin-releasing peptide analogue | SOD CONSEILS RECH APPLIC | 2015-12-02 | — | — | CN | disclosed |
| CN-101282738-B | Ghrelin analogs | IPSEN PHARMA S.A.S. (FR) | 2015-09-16 | — | — | CN | disclosed |
| WO-2008067831-A2 | USE OF GHRELIN, AN ANALOGUE THEREOF OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | CHARITE UNIVERSITÄTSMEDIZIN - BERLIN (DE) | 2008-06-12 | — | — | WO | disclosed |
| EP-1818061-A1 | Use of ghrelin for stimulating hair growth | Charite-Universitätsmedizin Berlin (DE) | 2007-08-15 | — | — | EP | disclosed |