SCHEMBL6257261

SCHEMBL6257261

O=[N+]([O-])c1[c]ccc(I)c1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.33
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32
P2RY6 Q15077 2/20 0.32
ADRA2A P08913 1/20 0.30
DRD5 P21918 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15208829 0.80 POLB (0.34) MEN1KMT2A
SCHEMBL26325 0.77 TSHR (0.48) LMNATSHR
SCHEMBL6904635 0.75 ALDH1A1 (0.44) LMNAMEN1KMT2ATSHR
SCHEMBL590426 0.75 TDP1 (0.44) LMNAMEN1KMT2ATSHRP2RY6
Water SCHEMBL28995322 0.75 TSHR (0.46) LMNATSHR
SCHEMBL387257 0.75 ALDH1A1 (0.44) LMNAMEN1KMT2ATSHR
SCHEMBL2131010 0.75 S100A4 (0.34) SNCALMNAMEN1KMT2ATSHR
SCHEMBL3044183 0.75 ALDH1A1 (0.44) LMNAMEN1HTTKMT2ATSHR
SCHEMBL441113 0.75 TSHR (0.45) LMNATSHR
SCHEMBL8650141 0.72 CYP19A1 (0.35) LMNAMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105142403-B For the method for pest control 住友化学株式会社 2018-06-19 CN disclosed
CN-105163587-B Compositions and methods for controlling pest 住友化学株式会社 2018-01-12 CN disclosed
CN-104955334-B The composition and method of pest control 住友化学株式会社 2017-12-29 CN disclosed
CN-103415510-B The preparation method of aminophenyl pyrimidyl alcohol derivate and synthetic intermediate thereof IHARA CHEMICAL INDUSTRY CO.,LTD. (JP) 2016-01-13 CN disclosed
CN-105163587-A Pest-control composition and pest-control method SUMITOMO CHEMICAL CO 2015-12-16 CN disclosed
CN-102443030-B The Nucleotide of the labeled nucleotide that light can rupture and nucleosides and mark and nucleosides and its using method in DNA sequencing LASERGEN INC. (US) 2015-12-16 CN disclosed
CN-105142403-A Pest-control method SUMITOMO CHEMICAL CO 2015-12-09 CN disclosed
CN-104968203-A Compositions and methods for controlling pests SUMITOMO CHEMICAL CO 2015-10-07 CN disclosed
CN-104955334-A PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD SUMITOMO CHEMICAL CO 2015-09-30 CN disclosed
WO-2014194250-A2 NOVEL NANOCARRIER DELIVERED CANCER CHEMOTHERAPEUTIC AGENTS UNIVERSITY OF CINCINNATI (US) 2014-12-04 WO disclosed
CN-103717598-A Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL CO 2014-04-09 CN disclosed
CN-103415510-A Method for producing aminophenyl pyrimidinyl alcohol derivative, and synthesis intermediate thereof IHARA CHEMICAL IND CO 2013-11-27 CN disclosed
CN-102443030-A Photocleavable labeled nucleotides and nucleosides and methods of use thereof in DNA sequencing LASERGEN INC 2012-05-09 CN disclosed
CN-102264917-A NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING 2011-11-30 CN disclosed
CN-102159543-A Novel triazolo [4,3-a ] pyridine derivatives, process for their preparation, their use as medicaments, pharmaceutical compositions and novel use, in particular as MET inhibitors SANOFI AVENTIS 2011-08-17 CN disclosed
CN-101636406-A Photocleavable labeled nucleotides and nucleosides and methods of use thereof in DNA sequencing LASERGEN INC 2010-01-27 CN disclosed
US-6951720-B2 Use of phosphorothiolate polynucleotides in ligating nucleic acids SAN DIEGO STATE UNIVERSITY FOUNDATION (US) 2005-10-04 US disclosed
EP-1572886-A2 USE OF PHOSPHOROTHIOLATE POLYNUCLEOTIDES IN LIGATING NUCLEIC ACIDS San Diego State University Foundation (US) 2005-09-14 EP disclosed
US-20030165841-A1 Use of phosphorothiolate polynucleotides in ligating nucleic acids NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-09-04 US disclosed
WO-2002090522-A2 USE OF PHOSPHOROTHIOLATE POLYNUCLEOTIDES IN LIGATING NUCLEIC ACIDS SAN DIEGO STATE UNIVERSITY FOUNDATION (US) 2002-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030165841-A1 Use of phosphorothiolate polynucleotides in ligating nucleic acids TYMP, TK1, DNTT SNCA 3460/4885LMNA 2332/4885MEN1 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.