Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26325 | 0.77 | TSHR (0.48) | ALDH1A1TSHRALOX15GPR35TP53 | |
| Water SCHEMBL28995322 | 0.75 | TSHR (0.46) | ALDH1A1TSHRALOX15GPR35TP53 | |
| SCHEMBL6257261 | 0.75 | SNCA (0.33) | TSHRMEN1LMNAHTTKMT2A | |
| SCHEMBL387257 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1FBP1MEN1 | |
| SCHEMBL441113 | 0.75 | TSHR (0.45) | ALDH1A1TSHRGPR35MAPK1FBP1 | |
| SCHEMBL590426 | 0.75 | TDP1 (0.44) | ALDH1A1TSHRSMN1; SMN2FBP1HIF1A | |
| SCHEMBL2131010 | 0.75 | S100A4 (0.34) | ALDH1A1TSHRCYP3A4MEN1LMNA | |
| SCHEMBL6904635 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRALOX15MAPK1CYP3A4 | |
| SCHEMBL8121072 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL4827704 | 0.75 | CASP6 (0.50) | TSHRTP53MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768796-A | Novel pyrazole-3-carboxamide derivative and preparation method and application thereof | 河北农业大学 | 2023-09-19 | — | — | CN | claimed |
| CN-115531610-A | Fiber composite membrane, preparation method and application thereof | 贵州医科大学附属医院 | 2022-12-30 | — | — | CN | claimed |
| EP-0960084-A1 | NOVEL SOLID-PHASE SYNTHESIS TECHNIQUES FOR PREPARING MULTIPLE ANALOGOUS COMPOUNDS | AXYS PHARMACEUTICALS, INC. (US) | 1999-12-01 | — | — | EP | claimed |
| WO-1998033751-A1 | NOVEL SOLID-PHASE SYNTHESIS TECHNIQUES FOR PREPARING MULTIPLE ANALOGOUS COMPOUNDS | AXYS PHARMACEUTICALS, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| CN-116768796-A | Novel pyrazole-3-carboxamide derivative and preparation method and application thereof | 河北农业大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-115531610-A | Fiber composite membrane, preparation method and application thereof | 贵州医科大学附属医院 | 2022-12-30 | — | — | CN | disclosed |
| CN-113121517-A | Triazole derivative and preparation method and application thereof | 中山大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-108760707-B | Application of probe reagent | 贵州大学 | 2021-02-02 | — | — | CN | disclosed |
| US-8362243-B2 | Method for selective localization of active agents at and in mitochondria and corresponding active agents | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2013-01-29 | — | — | US | disclosed |
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | UGICHEM GESELLSCHAFT FUER ORGANISCHE CHEMIE MBH (AT) | 2010-01-14 | — | — | US | disclosed |
| CN-101547934-A | Process for selectively localizing active ingredients on and in mitochondria and corresponding active ingredients | UGICHEM GES FUER ORGANISCHE CH (AT) | 2009-09-30 | — | — | CN | disclosed |
| EP-0960084-A1 | NOVEL SOLID-PHASE SYNTHESIS TECHNIQUES FOR PREPARING MULTIPLE ANALOGOUS COMPOUNDS | AXYS PHARMACEUTICALS, INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998033751-A1 | NOVEL SOLID-PHASE SYNTHESIS TECHNIQUES FOR PREPARING MULTIPLE ANALOGOUS COMPOUNDS | AXYS PHARMACEUTICALS, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| US-4463173-A | ANTIBIOTIC, BACTERICIDE | ICI PHARMA (FR) | 1984-07-31 | — | — | US | disclosed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | disclosed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009895-A1 | METHOD FOR SELECTIVE LOCALIZATION OF ACTIVE AGENTS AT AND IN MITOCHONDRIA AND CORRESPONDING ACTIVE AGENTS | TFB2M, TFAM, SHMT2 | ALDH1A1 2418/4885TSHR 3533/4885ALOX15 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.