Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 4/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | ALDH2 | P05091 | 7/20 | 0.61 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738641 | 0.87 | PARK7 (0.77) | PARK7CHRM5CHRM3ALDH1A1ALDH2 | |
| SCHEMBL30774299 | 0.86 | PARK7 (0.82) | PARK7CHRM5CHRM3ALDH1A1ALDH2 | |
| SCHEMBL4739092 | 0.86 | PARK7 (0.82) | PARK7CHRM5CHRM3ALDH1A1ALDH2 | |
| SCHEMBL4738025 | 0.84 | PARK7 (0.78) | PARK7CHRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL22589373 | 0.84 | PARK7 (0.78) | PARK7CHRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL20874420 | 0.83 | PARK7 (0.80) | PARK7CHRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL4736390 | 0.83 | PARK7 (1.00) | PARK7CHRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL4739934 | 0.83 | PARK7 (0.76) | PARK7CHRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL4736331 | 0.82 | PARK7 (0.75) | PARK7CHRM5CHRM3ALDH1A1ALDH2 | |
| SCHEMBL30937985 | 0.81 | ACHE (0.77) | PARK7CHRM5CHRM3ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125961-A | 1- (4-Trifluoromethyl-benzyl) -isatin derivative and preparation method and application thereof | 武汉大学人民医院（湖北省人民医院） | 2024-06-04 | — | — | CN | disclosed |
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |