Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.76 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.76 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.70 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.70 |
| ▸ | F3 | P13726 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | USP7 | Q93009 | 1/20 | 0.59 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
| ▸ | GABRP | O00591 | 1/20 | 0.59 |
| ▸ | GABRD | O14764 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800384 | 1.00 | PTPN1 (0.76) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL5796496 | 0.91 | ALOX5 (0.78) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL5796497 | 0.91 | ALOX5 (0.78) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL5013122 | 0.91 | PTPN1 (0.78) | PTPN1ALOX5AKR1B10AKR1B1PYGM | |
| SCHEMBL1051068 | 0.91 | PTPN1 (0.78) | PTPN1ALOX5AKR1B10AKR1B1PYGM | |
| SCHEMBL4736386 | 0.91 | PTPN1 (0.77) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL4736389 | 0.88 | PTPN1 (0.73) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL16704696 | 0.88 | PTPN1 (0.83) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL17332299 | 0.88 | PTPN1 (0.83) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| Arjunolic Acid SCHEMBL24135094 | 0.86 | PTPN1 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235078-A1 | Insulin secretion potentiator | USE-TECHNO CORPORATION | 2006-10-19 | — | — | US | disclosed |
| EP-1674089-A1 | ACCELERATOR FOR INITIAL INSULIN SECRETION | Use-Techno Corporation (JP) | 2006-06-28 | — | — | EP | disclosed |
| WO-2006054370-A1 | GLUCONEOGENESIS INHIBITING AGENT | USE-TECHNO CORPORATION (JP) | 2006-05-26 | — | — | WO | disclosed |
| US-20050143464-A1 | With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts | USE-TECHNO CORPORATION | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143464-A1 | With low side effects, which rapidly stimulate early insulin secretion and suppress blood glucose increase only at mealtimes; antidiabetic agent; triterpene acids or alcohols with picene ring; corosolic acids; oleanene acids; ursenoic acids; banaba plant extracts | GPR119, IRS1, AMY1A | PTPN1 1873/4885ALOX5 511/4885AKR1B10 1998/4885 |
| US-20060235078-A1 | Insulin secretion potentiator | IAPP, GPR119, IRS1 | PTPN1 1481/4885ALOX5 3951/4885AKR1B10 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.