Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086933 | 0.94 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC2HDAC11 | |
| SCHEMBL13094271 | 0.82 | ITGB3 (0.66) | FURINITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL30314839 | 0.81 | ITGB3 (0.64) | FURINITGB3ITGA2B | |
| SCHEMBL13094273 | 0.79 | ITGB3 (0.66) | FURINITGB3ITGA2B | |
| SCHEMBL4734594 | 0.78 | CA1 (0.50) | FURINHDAC1HDAC2ALDH1A1POLB | |
| SCHEMBL3090027 | 0.78 | FURIN (0.51) | FURINHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL7907566 | 0.78 | RAB9A (0.58) | KDM4ECYP3A4ALDH1A1POLB | |
| SCHEMBL3093114 | 0.78 | ITGB3 (0.64) | FURINITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL30701848 | 0.78 | ITGB3 (0.64) | FURINITGB3ITGA2B | |
| SCHEMBL8502841 | 0.78 | ITGB3 (0.68) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070831-A2 | BISBENZAMIDINES AND BISBENZAMIDOXIMES FOR THE TREATMENT OF HUMAN AFRICAN TRYPANOSOMIASIS | XAVIER UNIVERSITY OF LOUISIANA (US) | 2008-06-12 | — | — | WO | disclosed |