Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | AGXT | P21549 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454548 | 0.95 | IDO1 (0.56) | IDO1AGXTMAOBTDP1L3MBTL1 | |
| SCHEMBL19049283 | 0.90 | IDO1 (0.61) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL23640522 | 0.87 | IDO1 (0.57) | IDO1AGXTMAOBTDP1L3MBTL1 | |
| SCHEMBL649009 | 0.86 | PLA2G4B (0.45) | TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7387588 | 0.84 | IDO1 (0.54) | IDO1AGXTMAOBTDP1L3MBTL1 | |
| SCHEMBL7753392 | 0.84 | LTA4H (0.57) | TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7558489 | 0.84 | IDO1 (0.54) | IDO1AGXTMAOBTDP1L3MBTL1 | |
| SCHEMBL3768643 | 0.84 | IDO1 (0.71) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL2091873 | 0.83 | IDO1 (0.61) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL7386591 | 0.83 | IDO1 (0.53) | IDO1AGXTMAOBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008049651-A1 | PERFORMANCE-ENHANCED COSMETIC COMPOSITIONS WITH PURINE AND/OR PURINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2008-05-02 | — | — | WO | disclosed |