SCHEMBL301748

SCHEMBL301748

CCOC(=O)c1ccc(C)cc1C(=O)OCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.64
CA12 O43570 2/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA14 Q9ULX7 2/20 0.58
ALDH1A1 P00352 6/20 0.50
KDM4E B2RXH2 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
RAB9A P51151 3/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 2/20 0.50
L3MBTL1 Q9Y468 3/20 0.49
LMNA P02545 2/20 0.49
MAPK1 P28482 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1206020 0.91 TSHR (0.58) TSHRCA12CA1CA2CA7
SCHEMBL4628177 0.88 TSHR (0.51) TSHRCA12CA1CA2CA7
SCHEMBL4628668 0.88 ALDH1A1 (0.60) TSHRCA12CA1CA2CA7
SCHEMBL6912120 0.88 TSHR (0.63) TSHRCA12CA1CA2CA7
SCHEMBL4627939 0.88 TSHR (0.51) TSHRCA12CA1CA2CA7
SCHEMBL7222675 0.87 TSHR (0.53) TSHRCA12CA1CA2CA7
SCHEMBL15675411 0.87 ALDH1A1 (0.65) TSHRCA12CA1CA2CA7
SCHEMBL4834369 0.86 MEN1 (0.60) TSHRCA12CA1CA2CA7
SCHEMBL1107151 0.86 MEN1 (0.60) TSHRCA12CA1CA2CA7
SCHEMBL29668381 0.86 MEN1 (0.60) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1209172-B1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2008-07-02 EP claimed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US claimed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US claimed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP claimed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP claimed
US-12060378-B2 Solid catalyst component for olefin polymerization, method for producing solid catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization and method for producing polymer of olefin TOHO TITANIUM CO., LTD. (JP) 2024-08-13 US disclosed
US-20240218087-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN, POLYMER OF OLEFIN, METHOD FOR PRODUCING PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-07-04 US disclosed
EP-4349874-A1 OLEFIN POLYMERIZATION SOLID CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, MANUFACTURING METHOD FOR OLEFIN POLYMER, OLEFIN POLYMER, MANUFACTURING METHOD FOR PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-04-10 EP disclosed
EP-3645625-B1 HIGH STIFFNESS POLYPROPYLENE IMPACT COPOLYMER EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-03-27 EP disclosed
CN-117425682-A Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, process for producing olefin polymer, process for producing propylene block copolymer, and propylene block copolymer 东邦钛株式会社 2024-01-19 CN disclosed
US-11732067-B2 High stiffness polypropylene impact copolymer EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-22 US disclosed
CN-115867395-A Method for producing Mg-containing particles 东邦钛株式会社 2023-03-28 CN disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed
EP-0755914-B1 Process for producing isobenzofurandiones BAYER AG (DE) 1999-10-06 EP disclosed
US-5672719-A Process for the preparation of isobenzofurandiones BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed
EP-0755914-A1 Process for producing isobenzofurandiones BAYER AG (DE) 1997-01-29 EP disclosed
US-5482971-A Beta3 -adrenergic agents and their use in pharmaceutical compositions AMERICAN CYANAMID COMPANY (US) 1996-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12060378-B2 Solid catalyst component for olefin polymerization, method for producing solid catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization and method for producing polymer of olefin EEF2, ELL, POF1B TSHR 3311/4885CA12 524/4885CA1 651/4885
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX TSHR 4817/4885CA12 2609/4885CA1 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.