Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 6/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738700 | 0.85 | MAPK14 (0.39) | CNR2MLNRMAPK14ALDH1A1KDM4E | |
| SCHEMBL4737955 | 0.85 | OPRM1 (0.43) | MAPK14ALDH1A1KDM4ETSHRPDK1 | |
| SCHEMBL4734783 | 0.84 | OPRM1 (0.40) | MAPK14ALDH1A1KDM4ETSHRHTR1A | |
| SCHEMBL4734903 | 0.82 | KDM4E (0.41) | MAPK14ALDH1A1KDM4ETSHRHTR1A | |
| SCHEMBL4786222 | 0.82 | KDM4E (0.49) | MAPK14ALDH1A1KDM4ETSHRHTR1A | |
| SCHEMBL4734158 | 0.82 | DRD4 (0.43) | MAPK14ALDH1A1KDM4ETSHRHTR1A | |
| SCHEMBL4738192 | 0.81 | HRH3 (0.42) | MAPK14TSHROPRM1OPRK1 | |
| SCHEMBL4736796 | 0.80 | OPRM1 (0.49) | ALDH1A1KDM4ETSHRHTR1ADRD2 | |
| SCHEMBL4739217 | 0.79 | MEN1 (0.42) | MAPK14ALDH1A1KDM4ETSHRCXCR2 | |
| SCHEMBL4738789 | 0.79 | OPRM1 (0.49) | ALDH1A1KDM4ETSHRHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |