Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731194 | 0.84 | ITGA4 (0.42) | SIGMAR1TMEM97ITGB1ITGA4 | |
| SCHEMBL4734887 | 0.84 | ITGA4 (0.42) | SIGMAR1TMEM97ITGB1ITGA4 | |
| SCHEMBL4735544 | 0.82 | ITGB1 (0.53) | ITGB1ITGA4 | |
| SCHEMBL4736037 | 0.80 | SIGMAR1 (0.44) | SIGMAR1TMEM97ITGB1ITGA4AADAT | |
| SCHEMBL4736594 | 0.80 | SIGMAR1 (0.44) | SIGMAR1TMEM97ITGB1ITGA4AADAT | |
| SCHEMBL4735453 | 0.80 | ITGA4 (0.40) | SIGMAR1TMEM97ITGB1ITGA4 | |
| SCHEMBL4734792 | 0.80 | ITGA4 (0.40) | SIGMAR1TMEM97ITGB1ITGA4 | |
| SCHEMBL4734652 | 0.76 | SCN9A (0.46) | SIGMAR1TMEM97ITGB1ITGA4 | |
| SCHEMBL4730922 | 0.76 | SCN9A (0.46) | SIGMAR1TMEM97ITGB1ITGA4 | |
| SCHEMBL4733132 | 0.74 | ITGB1 (0.52) | SIGMAR1TMEM97ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |