Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 17/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 17/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736084 | 0.83 | ITGA4 (0.62) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL4736103 | 0.83 | ITGA4 (0.62) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL4732547 | 0.83 | ITGA4 (0.62) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL4734892 | 0.82 | SIGMAR1 (0.39) | ITGB1ITGA4 | |
| SCHEMBL4733969 | 0.80 | ITGA4 (0.54) | ITGB1ITGA4MEN1KMT2APDE4B | |
| SCHEMBL4730854 | 0.77 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL4730816 | 0.77 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL4735182 | 0.74 | ITGB1 (0.55) | ITGB1ITGA4MEN1KMT2APDE4B | |
| SCHEMBL4735900 | 0.72 | ITGB1 (0.70) | ITGB1ITGA4CYP3A4CYP2C9 | |
| SCHEMBL4737683 | 0.72 | ITGB1 (0.70) | ITGB1ITGA4CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |