Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121771 | 0.77 | LMNA (0.39) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11996532 | 0.75 | MCL1 (0.43) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2038041 | 0.74 | — | — | |
| SCHEMBL11041636 | 0.73 | F2R (0.32) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL26487698 | 0.72 | TPSAB1 (0.42) | — | |
| SCHEMBL14241657 | 0.71 | HPGD (0.38) | POLBSMN1; SMN2 | |
| SCHEMBL5987745 | 0.71 | MCL1 (0.47) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL24427061 | 0.70 | — | — | |
| SCHEMBL1768680 | 0.70 | GFPT1 (0.41) | — | |
| SCHEMBL1768678 | 0.70 | GFPT1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |