Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899145 | 0.80 | ERCC1 (0.46) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4786062 | 0.79 | RAB9A (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4736170 | 0.78 | KMT2A (0.58) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4738890 | 0.77 | KMT2A (0.51) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4738664 | 0.76 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4739350 | 0.76 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4739765 | 0.75 | RAB9A (0.46) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4737872 | 0.75 | KMT2A (0.51) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL259629 | 0.73 | RAB9A (0.59) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL3159586 | 0.73 | RAB9A (0.59) | KMT2AKDM4EMEN1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |
| US-4620009-A | CATALYTIC REDUCTION OF IMIDAZOLIN ONE DERIVATIVE | CYANAMID AGRICULTURAL DE PUERTO RICO, INC. (US) | 1986-10-28 | — | — | US | disclosed |
| US-4370482-A | Synthesis of tetramisole, levamisole and their derivatives | AMERICAN CYANAMID CO. (US) | 1983-01-25 | — | — | US | disclosed |
| US-4314066-A | PREPARATION OF 1-(2-SUBSTITUTED ETHYL)-4-PHENYL-2-IMIDAZOLIDONES AND IMIDAZOLIDINE-2-THIONESC HYDROGENATION, CHIRAL CATALYST, HYDROLYSIS, SULFURIZATION | AMERICAN CYANAMID CO. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4310672-A | Synthesis of intermediates for tetramisole, levamisole and their derivatives | AMERICAN CYANAMID CO. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4139707-A | ANTHELMINTICS | AMERICAN CYANAMID COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
| US-4090025-A | ALKOXYETHYL-PHENYL-IMIDAZOLIN-2-ONES OR 2-IMIDAZOLIDONES OR IMIDAZOLIDINE-2-THIONES | AMERICAN CYANAMID COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4087611-A | CHEMICAL INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1978-05-02 | — | — | US | disclosed |