Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735233 | 0.77 | KMT2A (0.57) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4783037 | 0.74 | LMNA (0.43) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4739350 | 0.73 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4736170 | 0.72 | KMT2A (0.58) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL259629 | 0.71 | RAB9A (0.59) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4738664 | 0.70 | KMT2A (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4786062 | 0.70 | RAB9A (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4785588 | 0.68 | GFER (0.47) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL3169921 | 0.67 | RAB9A (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4738830 | 0.67 | KMT2A (0.61) | KMT2AKDM4EMEN1RECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |