Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | DBH | P09172 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737872 | 0.89 | KMT2A (0.51) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4739836 | 0.89 | KMT2A (0.49) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4740547 | 0.85 | DBH (0.53) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4738830 | 0.85 | KMT2A (0.61) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4738142 | 0.85 | CYP11B1 (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4738141 | 0.83 | RAB9A (0.46) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4739765 | 0.80 | RAB9A (0.46) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL9372580 | 0.79 | RAB9A (0.50) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4739723 | 0.79 | RAB9A (0.45) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4735233 | 0.78 | KMT2A (0.57) | KMT2AKDM4EMEN1RECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |