Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737583 | 0.90 | GAA (0.46) | MAPK14GAATSHRPDK1HTT | |
| SCHEMBL3826441 | 0.81 | MAPK14 (0.49) | MAPK14PDK1HCAR3 | |
| SCHEMBL4737107 | 0.80 | GAA (0.58) | MAPK14GAATSHRPDK1HTT | |
| SCHEMBL4737668 | 0.78 | GAA (0.56) | MAPK14GAATSHRPDK1HTT | |
| SCHEMBL4737592 | 0.78 | GAA (0.56) | MAPK14GAATSHRPDK1HTT | |
| SCHEMBL4735150 | 0.78 | TSHR (0.51) | MAPK14GAATSHRPDK1HTT | |
| SCHEMBL4733572 | 0.78 | TSHR (0.45) | MAPK14GAATSHRPDK1HTT | |
| SCHEMBL4737958 | 0.78 | TSHR (0.48) | MAPK14GAATSHRPDK1HTT | |
| SCHEMBL4787168 | 0.77 | TSHR (0.45) | MAPK14GAATSHRPDK1HTT | |
| SCHEMBL4738966 | 0.77 | GAA (0.54) | MAPK14GAATSHRPDK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |