Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737107 | 0.85 | GAA (0.58) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4738966 | 0.83 | GAA (0.54) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4737668 | 0.83 | GAA (0.56) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4786167 | 0.81 | GAA (0.51) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4738200 | 0.81 | GAA (0.51) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4735056 | 0.80 | GAA (0.50) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4737949 | 0.80 | GAA (0.52) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4738239 | 0.79 | TSHR (0.49) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4735150 | 0.79 | TSHR (0.51) | GAATSHRHTTMAPK14PTGDR2 | |
| SCHEMBL4737126 | 0.79 | TSHR (0.48) | GAATSHRHTTMAPK14PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |