Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271385 | 0.89 | L3MBTL1 (0.52) | ATMTDP1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL4803049 | 0.85 | ALDH1A1 (0.64) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL135162 | 0.85 | ATM (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL9324919 | 0.85 | ATM (1.00) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL134024 | 0.83 | ATM (0.95) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL134300 | 0.83 | ATM (0.95) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL44226 | 0.80 | CES1 (0.52) | ATMTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL27386832 | 0.80 | L3MBTL1 (0.72) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL4804883 | 0.80 | KMO (0.62) | TDP1MAPT | |
| SCHEMBL7637875 | 0.80 | TDP1 (0.51) | ATMTDP1L3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419312-B1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE 2-ARYL-PROPIONIC ACIDS | RHONE-POULENC SANTE (FR) | 1993-08-04 | — | — | EP | claimed |
| US-5097064-A | By reduction of arylacrylic acid using a rhodium derivative and water soluble chiral ligand as catalyst | RHONE-POULENC SANTE (FR) | 1992-03-17 | — | — | US | claimed |
| CN-114507320-B | Acrylate prepolymer and preparation method and application thereof | 嘉兴金门量子材料科技有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-114507320-A | Acrylate prepolymer and preparation method and application thereof | 嘉兴金门量子材料科技有限公司 | 2022-05-17 | — | — | CN | disclosed |
| WO-2008060844-A1 | POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE | ALBEMARLE CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |
| EP-0673911-B1 | Process for producing optically active carboxylic acids and chiral ligands for this purpose | TAKASAGO PERFUMERY CO LTD (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0529444-B1 | 2-Arylpropenic acids and their utilisation in the preparation of 5-ketoprofen | BAYER AG (DE) | 1997-04-16 | — | — | EP | disclosed |
| US-5563295-A | HYDROGENATION OF OLEFINIC CARBOXYLIC ACID USING RUTHENIUM-PHOSPHINE COMPLEX CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0673911-A1 | Process for producing optically active carboxylic acids and chiral ligands for this purpose | Takasago International Corporation (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5362907-A | Intermediates and their use in the preparation of s-ketoprofen | BAYER AKTIENGESELLSCHAFT (DE) | 1994-11-08 | — | — | US | disclosed |
| EP-0529444-A2 | 2-Arylpropenic acids and their utilisation in the preparation of 5-ketoprofen | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |
| US-5097064-A | By reduction of arylacrylic acid using a rhodium derivative and water soluble chiral ligand as catalyst | RHONE-POULENC SANTE (FR) | 1992-03-17 | — | — | US | disclosed |